The opposite of "most low ranking" can be expressed in various ways such as "highest-ranking," "superior," or "top-tier." These antonyms suggest a person or object that holds a relatively higher position, status, or importance. For example, a CEO is the highest-ranking executive in a company, an A+ grade is superior to a C-, and a luxury car can be considered top-tier compared to an economy car. These antonyms offer a way to differentiate individuals or things based on their level of significance, and they can affect how they are perceived by others. While "most low ranking" implies a certain level of humility or underperformance, its antonyms imply success, excellence, and achievement.