Antonyms, or words with opposite meaning, for the phrase "most mesmerized" can include disinterested, bored, unimpressed, indifferent, unconcerned, uninterested, detest, unengaged, and unmoved. These words indicate a lack of fascination or interest in a particular situation, object, or topic. For instance, one who is disinterested shows no interest in something or someone, and an unmoved individual stays emotionally unaffected by something that could have captivated others. Thus, finding the right antonym to "most mesmerized" can converse an altogether different message to the listener, demonstrating a change in emotion, interest or mental state of the speaker.