The word "most mystified" is best described as being confused, puzzled, or bewildered. Its antonyms are those that convey a sense of understanding, clarity, and enlightenment. These include words such as comprehended, understood, clarified, explained, and demystified. When one understands a situation, they are no longer mystified by it. To clarify a topic is to remove any confusion surrounding it, and to explain it is to make it easier to understand. Ultimately, being demystified removes any mystique or confusion surrounding something, and allows for true understanding to take place.