Most nimblewitted can be interpreted as a compliment or an insult, depending on the context. If you're looking for antonyms (words with opposite meanings), some options could be "dull-witted," "slow," "dense," "thick," "stupid," or "clumsy." It's important to note that these words can also have negative connotations and may not be the best choice in all situations. Instead, consider using more neutral or positive words like "thoughtful," "calculated," "intelligent," or "reflective." Ultimately, the antonym you choose will depend on the tone and intent of your message.