Most odds-on is a term used to refer to something that is highly likely to occur. Antonyms for the word "most odds-on" can include terms like "unlikely," "improbable," "doubtful," "uncertain," "unpredictable," and "risky." These words may be used to describe situations or events that are less likely to happen or have a lower probability of occurring. Examples of situations where these antonyms might apply include uncertain investment opportunities, improbable weather patterns, and risky ventures. By using antonyms for the term "most odds-on," individuals can express doubt or uncertainty about potential outcomes and make more informed decisions about their choices.