Most profaned is a phrase that refers to something that has been desecrated or blasphemed to the fullest extent. However, there are several antonyms that denote the opposite meaning, such as sanctified, consecrated, holy, or revered. To sanctify something means to make it sacred or hallowed, while to consecrate means to dedicate something to a sacred purpose. Holy signifies something that is purely devoted to a divine entity, while revered means something that is greatly admired and respected. Hence, these antonyms represent the polar opposite of the term most profaned, as they suggest sanctity, purity, and sacredness instead of desecration and blasphemy.