The antonyms for the phrase "most psyched out" can vary depending on the context in which it is used. Generally, "psyched out" means to be mentally or emotionally affected by something, often resulting in anxiety or distress. Hence, the antonyms can include phrases such as "at peace," "calm and collected," "relaxed," "unperturbed," "unfazed," or "composed." These terms denote a state of being free from mental or emotional disturbances, and they can be used to counteract the negative effects of feeling "psyched out." Practicing mindfulness, meditation, and deep breathing exercises are some ways to achieve a calm and centered state of mind.