The most pullulating refers to something that is extremely abundant or highly populated. However, there are many antonyms that describe the opposite of this word. Scant, sparse, and few are some antonyms that signify lesser abundance, while barren, desolate, and empty suggest a complete lack of any organisms or living beings. Another set of antonyms that could be used for most pullulating are quiet, calm, and serene. These words imply a peaceful and undisturbed environment, not teeming with life. The opposite of most pullulating portrays an environment that is less lively, less populated, and less abundant.