Antonyms for the word "most recuperative," which means to recover quickly, include least restorative, slowest healing, and least rejuvenating. Other antonyms are least revitalizing, least invigorating, and least regenerating. The opposite of most recuperative can also be described as non-renewing, non-rejuvenating, non-invigorating, and non-regenerating. The antonyms for most recuperative can be used to describe something that takes longer to recover from, or something that does not provide the energy or vitality needed to feel refreshed. It can also be used to describe a situation that does not provide health or wellness benefits, such as chronic stress or illness.