When it comes to describing someone as "most respected," there are many synonyms that can be used to convey the same sentiment. For example, you could describe them as highly esteemed, revered, greatly admired, venerated, or held in high regard. Other synonyms might include celebrated, renowned, honored, esteemed, or acclaimed, depending on the context in which the word is used. Ultimately, the specific synonym used will depend on the tone and meaning that the writer is trying to convey, but by using any of these words, the reader will understand that the subject is a person of great significance and esteemed reputation.