The phrase "most revitalizing" refers to something that is highly rejuvenating, reinvigorating, and refreshing. Its antonyms are words that mean the opposite; they denote things that are depleting, exhausting, and draining. The antonyms for most revitalizing include words such as punishing, tiring, exhausting, enervating, and fatiguing. These words signify things that take away energy instead of adding to it. Some other antonyms for the phrase "most revitalizing" include strenuous, demanding, draining, and sapping. It is important to understand the antonyms of revitalizing as it helps to become aware of what drains our energy and avoid those practices or habits.