Most sacramental is a term used to describe something that is very meaningful, holy, and important. However, there are several antonyms to describe the opposite of most sacramental. One of the most common antonyms is profane, which means something that is disrespectful or not holy. Another antonym is secular, which means something that is not related to religion or spiritual matters. Another antonym is mundane, which means something that is ordinary, unexciting, and not special. Additionally, another antonym is unimportant or trivial, which means something that is not significant or meaningful. In summary, there are several antonyms to describe the opposite of most sacramental.