The term "most second fiddle" implies someone or something that is not the primary focus, and is therefore subservient. Antonyms for this phrase include "leading role," "top billing," and "prominent position." When someone or something becomes the leading role, it not only assumes a top position but also takes control over the rest of the elements. For instance, a leader assumes a dominant role over his team. Similarly, occupying the top billing means that someone is receiving the most attention, whereas having a prominent position is indicative of importance or power. By using these antonyms, we can convey a sense of strength, power, and prominence over others.