The antonyms for "most seldom" would be "most frequently" or "most commonly". If something is "most seldom", it means that it occurs rarely, infrequently or almost never. On the other hand, if something is "most frequently", it means that it occurs often, regularly, or on a frequent basis. For example, the antonym of "most seldom vacation" would be "most frequently vacation". Similarly, the antonym of "most seldomly used word" would be "most commonly used word". By using antonyms, we can create effective contrasts, emphasize differences, and add variety to our writing, communicating our ideas effectively.