The phrase "most shrewdness" refers to the quality of being highly perceptive and astute, with the ability to make quick and calculated decisions. Synonyms for this phrase might include "sharpness," "cunning," "acumen," "savvy," "caginess," "ingenuity," "cunningness," "smartness," "astuteness," and "apprehension." These words all capture the same essence of "most shrewdness," emphasizing a combination of intelligence, practicality, and strategic thinking. Each of these synonyms has its own nuances, but all convey the idea of a person who is particularly skilled at understanding people and situations, and who is able to use this knowledge to their advantage.