The word "most squirming" implies uneasiness or discomfort, and its antonyms are words that convey calmness, poise, and confidence. Some of the antonyms for "most squirming" include composed, relaxed, serene, tranquil, comfortable, and confident. These words describe a person who is in control of their emotions and is at ease in any situation. It is essential to have these qualities in professional or personal life, as it makes one appear poised and confident. By using the opposite of "most squirming," one can convey a sense of strength and confidence, promoting stability and composure in circumstances of stress or nervousness.