The antonyms for the word "most straightup" include crooked, twisted, circuitous, convoluted, meandering, indirect, labyrinthine, and roundabout. These words represent the opposite of being clear and direct. They describe something that is complicated, deceptive, and difficult to follow. These words might refer to a path or journey that is full of twists and turns, a person who is not truthful, or a situation that is overly complicated. In contrast to being "most straightup," these antonyms signify confusion, complexity, and a lack of transparency. They add depth and nuance to our communication by providing an array of descriptive options that convey specific meanings.