The term "most toned-down" implies something that has been reduced in intensity, so antonyms for this phrase will be words that describe things that are more vigorous, pronounced, or emphasized. Some possible opposites of "most toned-down" include "most enhanced," "most lively," "most intensified," "most accentuated," and "most emphasized." Other antonyms could be "most vibrant," "most forceful," "most animated," "most striking," and "most potent." Each of these words suggests a different level of prominence or energy, conveying the opposite meaning of "most toned-down." Therefore, choosing the right antonym will depend on the context in which the phrase is used.