The opposite of "most top ranking" would be "least bottom ranking". This implies the lowest or worst position in a hierarchy or ranking system. Other antonyms for "most top ranking" include "least successful", "least accomplished", "least distinguished", and "least influential". These words suggest the opposite of superiority, prominence and excellence. Instead, they connote failure, inadequacy, and underperformance. It is important to note that antonyms for a specific word can vary depending on the context, emphasis, and intended meaning. Therefore, understanding the subtle differences between antonyms is essential for clear and effective communication.