Most well pleased is a term that signifies a state of happiness and contentment. However, in some scenarios, this phrase may not be suitable, and we need to use the opposite or antonyms to convey a different message. Some possible antonyms for most well pleased could be most disgruntled, most unsatisfied, most unhappy, most disappointed, or most displeased. These terms suggest a more negative outlook and could be useful in situations where there is a need to express discontentment, dissatisfaction, or unhappiness with a particular event, person, or outcome. Therefore, choosing the right antonyms to most well-pleased can help convey a more accurate and nuanced message.