MUPS stands for Medically Unexplained Physical Symptoms which refers to physical symptoms that have no apparent medical explanation. Synonyms for MUPS include somatic symptoms, functional somatic symptoms, and medically unexplained symptoms, to name a few. These terms are often used interchangeably in the medical community to describe patients who present with physical symptoms that cannot be attributed to a known medical condition. MUPS can be a challenging concept for healthcare providers to diagnose and treat, and it often requires a multidisciplinary approach to manage. Despite the lack of a definitive medical cause, patients with MUPS can experience significant impairments in their quality of life, making effective management critical.