When it comes to describing unpleasant people, there are numerous synonyms for the term "nasty people." Some common alternatives include individuals who are rude, mean, obnoxious, or unpleasant. Other synonyms include those who are spiteful, vindictive, or antagonistic, as well as those who are deceitful, manipulative, or dishonest. In some cases, people may be labeled as "difficult," "challenging," or "troublesome," while in others, they may be called "bullies," "jerks," or "villains." Ultimately, the choice of synonym depends on the specific behavior and qualities of the individual in question, but these options can provide a starting point for finding a more accurate and appropriate descriptor.