Nicotiana Rustica is a plant species that belongs to the tobacco family. This type of tobacco plant has several common synonyms, including Mapacho, Sacred Tobacco, and Aztec Tobacco. It is primarily grown in South America, particularly in Peru, Bolivia, and Brazil. Mapacho is considered a very potent and traditional species of tobacco and is used for spiritual and ceremonial purposes. It is sometimes used as a base for Ayahuasca, a traditional Amazonian plant medicine. Besides its spiritual use, Nicotiana Rustica leaves are also used for making cigarettes, snuff, and tobacco pipes. These various synonyms of Nicotiana Rustica are widely used depending on their cultural and traditional usage across regions.