Nissl bodies degeneration, also known as chromatolysis, refers to the disintegration of Nissl bodies, which are clusters of endoplasmic reticulum found in neuronal cell bodies. This phenomenon can occur due to various factors like trauma, injury, or disease, leading to functional disruption of the nerve cells. To describe this process, several synonyms are used interchangeably in scientific literature. Terms like cytoplasmic dissolution, neuronal changes, cell body alteration, or chromatolytic changes are often employed. These synonyms emphasize the significant morphological and biochemical alterations occurring within nerve cells during Nissl bodies degeneration. Understanding these synonyms aids researchers and clinicians in effectively communicating their findings and unraveling the underlying mechanisms of neuronal damage.