The phrase "of great consequence" typically refers to something that is very important or significant. However, there are many other ways to express this idea. Synonyms for "of great consequence" may include "critical", "crucial", "vital", "essential", "pivotal", "paramount", "significant", "major", "momentous", or "profound". Each of these words carries a slightly different connotation, but all convey a sense of importance or significance. Depending on the context in which the phrase is used, one of these synonyms may be more appropriate than others, so it's important to choose language that accurately reflects the intended meaning.