An open biopsy is a medical procedure that involves cutting open a part of the body to remove a tissue sample for examination. The term 'open' in open biopsy refers to the surgical incision made to access the affected area. However, there are other terms used in medical literature and clinical practice for open biopsy. Some common synonyms for open biopsy include surgical biopsy, incisional biopsy, cut biopsy, or core biopsy. These terms imply that a surgical incision is made to obtain the tissue sample. Other types of biopsy include needle biopsy, aspiration biopsy, and endoscopic biopsy, which do not require an incision.