Open Reading Frame (ORF) is a common term used in molecular biology to describe a sequence of DNA or RNA that can potentially encode a protein. However, there are several synonyms for ORF that may be used interchangeably, including coding sequence (CDS), reading frame, reading phase, or coding frame. These terms are all related to the genetic code and the process of translation, where the information contained within the DNA sequence is translated into a functional protein. By identifying ORFs or CDSs within a genome, researchers can better understand the biological functions of various genes and develop new treatments for genetic diseases.