Paget's disease, also known as osteitis deformans, is a chronic bone disorder characterized by the abnormal breakdown and formation of bone tissue. The condition is named after Sir James Paget, the 19th-century British physician who first described it. About 1-3% of people over the age of 50 are affected by Paget's disease, with men being affected more often than women. Some common synonyms for Paget's disease include osteodystrophia deformans, osteodystrophia deformans progressiva, Paget's disease of bone, and pagetoid bone disease. While there is no cure for Paget's disease, treatments such as bisphosphonates and calcitonin can help relieve symptoms and slow the progression of the condition.