Multiple sclerosis is a debilitating autoimmune disease that affects the central nervous system. Pathophysiology of multiple sclerosis refers to the underlying mechanisms that lead to the development and progression of this condition. Some possible synonyms for this term could include disease pathology, pathogenesis of multiple sclerosis, or the physiological abnormalities associated with MS. Other related terms may include the molecular biology of MS, the immunological factors involved, or the impact of environmental triggers on the disease process. Despite ongoing research into the pathophysiology of MS, much remains to be understood about its complex mechanisms and the best strategies for treatment and prevention.