Perleche is a term used to describe a condition commonly known as angular cheilitis. This condition causes inflammation in the corners of the mouth, leading to soreness, redness, and sometimes even cracking. There are several synonyms that are used interchangeably with perleche, including cheilosis, angular stomatitis, and angular leukoplakia. Additionally, some people may refer to it as "corner of the mouth sores." The condition is typically caused by factors such as bacterial or fungal infection, poor nutrition, dehydration, or a compromised immune system. Treatment options include using topical creams, improving oral hygiene, and addressing any underlying medical conditions that may be contributing to the problem.