Plaquenil is a medication commonly used to treat malaria and autoimmune diseases such as rheumatoid arthritis and lupus. Some of the synonyms for Plaquenil include Hydroxychloroquine, Quinoric, Axemal, Dolquine, and HCQS. These medications work by reducing inflammation in the body and blocking the action of certain immune cells that contribute to the disease process. While these medications are generally safe and well-tolerated, they can have side effects such as nausea, diarrhea, and headache. Therefore, it is important to follow proper medication dosing and monitor for any allergic reactions or adverse effects. With proper medical guidance, patients can effectively manage their autoimmune conditions and improve their quality of life.