Pneumococcal Polysaccharide Vaccine is a biologic drug that has numerous synonyms due to its complex scientific name. It is commonly referred to as PPV, pneumococcal vaccine, or pneumonia shot. Additionally, different brands of this vaccine have different names, such as Prevnar 13 or Pneumovax 23. This vaccine serves as a preventive measure to various bacterial infections caused by Streptococcus pneumoniae and is typically administered to high-risk individuals, such as the elderly and people with weakened immune systems. Regardless of its name, the vaccine is crucial in protecting millions of people around the world from severe pneumococcal infections.