Poirier’s line is a medical term used to describe a crease on the earlobe that is often associated with cardiovascular disease. Also known as Frank’s sign or diagonal earlobe crease, this distinct mark has garnered attention due to its potential correlation with heart health. Understanding these synonyms helps in identifying this physiological clue, as it may hint at underlying conditions. Although the appearance of a creased earlobe alone is not conclusive evidence of heart problems, it serves as a visual cue requiring further examination. Hence, recognizing the various terms associated with Poirier’s line increases awareness regarding this potential risk factor and encourages individuals to seek appropriate medical attention if necessary.