Pre-exposure prophylaxis (PrEP) is a preventive measure used to reduce the risk of acquiring HIV. Other terms that are synonymous with PrEP include HIV prevention medication, pre-emptive HIV treatment, HIV pre-exposure prophylaxis, and pre-emptive HIV prevention. PrEP involves taking a daily medication to prevent HIV infection from sexual or injection drug use. Individuals who are at high risk for acquiring HIV may use PrEP as a preventive measure. The use of PrEP has been shown to be highly effective in reducing the risk of HIV infection when used consistently and correctly. PrEP is an important tool in the fight against HIV, and individuals can talk to their healthcare provider about whether PrEP is right for them.