Prefrontal leukotomy is a psychiatric procedure that was once used to treat severe mental illnesses such as schizophrenia and depression. However, due to the invasive nature of the procedure and a lack of sufficient scientific evidence supporting its effectiveness, it is no longer a commonly used treatment. There are several synonyms that can be used to refer to prefrontal leukotomy, including lobotomy, frontal lobotomy, prefrontal lobotomy, and leukotomy. Although these terms all refer to the same procedure, they are distinct in the way they highlight different aspects of the process. Nowadays, alternative treatments such as medication and psychotherapy are often used instead of prefrontal leukotomy.