Primary Ciliary Dyskinesia (PCD) is a rare genetic disease that affects the motility of cilia. It is also known as immotile ciliary syndrome, ciliary aplasia or hypoplasia, and Kartagener syndrome. The condition is characterized by recurrent respiratory tract infections, chronic sinusitis, and bronchiectasis. Patients with PCD may also experience infertility due to impaired mobility of spermatozoa and reduced or absent female fertility. The diagnosis of PCD is based on clinical symptoms, immunofluorescence testing, and genetic analysis. Treatment includes antibiotics to control infections, airway clearance techniques, and surgery for severe cases. Early diagnosis and prompt treatment can improve the quality of life of PCD patients.