The word "pro-nest" means in favor of creating a safe and comfortable home environment. Its antonyms, therefore, are words that denote the opposite. Some suitable antonyms for "pro-nest" include words like anti-domestic, anti-nurturing, anti-homey, and anti-comfortable. These antonyms can also be expressed using phrases such as anti-homemaking or anti-domesticity. These words indicate a lack of preference for the establishment and maintenance of a comfortable and loving home environment. Instead, they suggest a preference for the hustle and bustle of the outside world, with no special attachment to a specific place as home.