Progressive Supranuclear Ophthalmoplegias (PSOs) refer to a group of rare neurological disorders characterized by the progressive impairment of eye movement control. Synonyms for PSOs include Supranuclear Palsy, Progressive Supranuclear Palsy, and Steele-Richardson-Olszewski Syndrome. These conditions share common symptoms such as difficulty in voluntary eye movements, problems with balance and coordination, and cognitive decline. PSOs are caused by the deterioration of certain areas within the brain, leading to the dysfunction of eye muscles and other motor functions. While there is currently no cure for PSOs, treatments aim to alleviate symptoms and improve quality of life for affected individuals. Early diagnosis and proper management play crucial roles in managing these challenging conditions.