There are several words that can be used as synonyms for the phrase "prudent course." One such word is "wise decision," which indicates a thoughtful and careful approach to choosing a course of action. Another option is "judicious choice," which implies a careful consideration of the potential outcomes and risks involved in a given situation. Additional synonyms for "prudent course" include "practical option," "sensible choice," and "cautious approach." Each of these words suggests a level of attention to detail and a desire to make the best possible decision given the circumstances at hand.