The antonyms for the word "pure-bred" are many, and they signify anything that is not pure, but rather mixed or hybrid. A few antonyms of pure-bred are impure, non-pure, crossbred, mongrel, and hybrid. Each of these words delivers a different connotation, depending on the context in which it is used. For instance, hybrid may refer to something that is crossbred or mixed, but with a desirable attribute. On the other hand, impure or non-pure may indicate that something is diluted, flawed or deficient. Regardless of the usage, the antonyms of pure-bred are essential to describing many things in our world, including animals, plants, and even people.