Quinckes edema, also known as angioedema, is a condition characterized by swelling under the skin, particularly around the face, lips, tongue, throat, and sometimes the genitals and extremities. This can cause severe pain, difficulty breathing, and even death in some cases. There are a few synonyms for this condition, such as giant urticaria, giant hives, and angioneurotic edema. The word "angio" is derived from the Greek word "angeion" meaning "vessel" and "edema" refers to swelling. This condition can be triggered by a variety of factors, including allergic reactions, hereditary factors, and certain medications. It is important to seek medical attention immediately if you experience any symptoms of Quinckes edema.