The phrase "real issues" can be replaced by a variety of synonyms depending on the context. Some alternatives include "pressing concerns," "critical problems," "significant challenges," "genuine dilemmas," "authentic struggles," or "actual difficulties." Each option emphasizes the urgency and importance of the topic at hand, indicating that it is not trivial or insignificant. These synonyms also allow writers and speakers to vary their language, creating more engaging and dynamic discourse. Ultimately, the choice of word depends on the specific situation and audience, but all of these options convey the gravity and relevance of the issue being discussed.