Rephosphorylation refers to the process of adding a phosphate group to a molecule that has already been phosphorylated. Some synonyms for rephosphorylation include phosphorilation renewal, reactivation of phosphorylation, and phosphorylation regeneration. Other words that are often used in place of rephosphorylation include phosphorylation reversal, phosphorylation recycling, and re-energizing of phosphorylation. Regardless of the term used, the process involves the addition of a phosphate molecule to a substrate to renew its ability to function within a cell. This process is critical for various cellular functions and is essential for maintaining overall cellular health and homeostasis.