RNA silencing is a process that involves sequence-specific gene silencing mediated by the RNA interference pathway. It is a complex process that plays a crucial role in regulating gene expression and maintaining genome stability across species. Synonyms for RNA silencing include post-transcriptional gene silencing, RNA interference, small RNA-mediated gene silencing, and small RNA-induced gene silencing. These terms are used interchangeably in research related to various fields such as molecular biology, genetics, and biotechnology. The study of RNA silencing has opened up new avenues for the treatment of diseases caused by aberrant gene expression, and researchers continue to explore its potential for disease therapy.