Romano- is a prefix that originates from the Latin language and is usually associated with things related to Rome or the Roman Empire. Some common synonyms for Romano- include Romanesque, which refers to a type of architecture that was common during the medieval times in Europe and borrowed heavily from Roman architecture. Another synonym is Roman, which refers to the people or culture of Rome. The word Romance, on the other hand, refers to a series of languages that are closely related to Latin and are spoken in various parts of Europe. Overall, the prefix Romano- is widely used in different contexts to describe things that have a historical or cultural connection to Rome and its empire.