The term "run-of-the-mine" is used to describe something that is ordinary, typical, or average. Its antonyms are words that connote something unusual, exceptional, or outstanding. Some of the antonyms for "run-of-the-mine" are remarkable, extraordinary, excellent, exceptional, outstanding, unique, superior, exclusive, and special. These words describe something that is not just ordinary but exceptional that stands out from the crowd. The use of such antonyms is common when describing individuals, products, services or experiences that are unique or superior in their respective fields. Therefore, these antonyms can give a more impactful description of something that is exceptional or beyond the norm.