Schapiros sign, also known as Schapiro's syndrome or Schapiro's reflex, refers to a clinical sign observed during neurological examinations. It is characterized by a transient or sustained resistance to passive extension of the fingers upon flexion of the wrist. This resistance is mainly due to involuntary contraction of the flexor muscles, commonly seen in individuals with upper motor neuron lesions. While there are no direct synonyms for Schapiros sign, it can also be described as an abnormal flexor response or increased resistance to wrist extension. Identifying and understanding this sign can aid healthcare professionals in diagnosing various neurological conditions.