Sequencing by hybridization is a process in which probes are designed to hybridize with target DNA fragments. This approach is commonly used in genome sequencing, where it allows for the identification of specific nucleotide sequences. However, there are several other synonyms that can be used to describe this process. For example, sequencing by hybridization is sometimes called array-based sequencing or oligonucleotide hybridization. Other similar terms include hybridization-based sequencing, array sequencing, and DNA chip sequencing. Regardless of the name, sequencing by hybridization is an important technique in molecular biology and genomics research, and has numerous applications in fields such as medicine and biotechnology.