Serum Response Factor (SRF) is a vital molecular regulator involved in various cellular processes. Synonymously referred to as c-fos serum response element-binding protein (CF2), MADS box transcription enhancer factor 2 (MEF2) or megakaryoblastic leukemia 1 (MKL1), SRF plays a crucial role in transducing extracellular signals into gene expression responses. It acts as a transcription factor, binding to serum response elements (SREs) in the promoter region of target genes. These SRF-associated synonyms highlight the importance of this protein in orchestrating cellular activities like proliferation, differentiation, and migration. Understanding the various ways to address SRF enhances our comprehension of its multifaceted functions in biological systems.