When it comes to describing someone who is sharp-tongued, there are a plethora of synonyms to choose from. Some possible options include acerbic, biting, caustic, cutting, sarcastic, snarky, and sardonic. Each of these words suggests a certain level of wit or humor, but also carries connotations of criticism, disdain, or even cruelty. Other similar words might include blunt, frank, or direct, but those tend to suggest a more straightforward approach rather than a witty one. Ultimately, the choice of synonym will depend on the specific context and the tone one wishes to convey.